Profile of Isaac M. Held
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چکیده
منابع مشابه
Profile of Helen M. Blau.
The human ability to regenerate tissues is crucial to survival: wounds heal, broken bones knit, and livers regrow. However, the quality and length of life are constrained by limitations in this ability. Cardiac muscles do not regrow after infarction, and other damaged muscles rebuild with difficulty, especially with age. Stanford University stem cell biologist Helen M. Blau has devoted her care...
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As a young doctoral candidate at the Johns Hopkins University School of Medicine, David M. Sabatini was allowed to choose his own research project for his thesis. He chose to investigate the molecular mechanism of rapamycin, a compound with antifungal, antitumor, and immunosuppressant properties. The decision was pivotal, because Sabatini went on to discover the mechanistic target of rapamycin ...
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Whether he is restoring his 1976 Triumph TR6 British roadster or analyzing proteins, James Berger is curious about how machines work and what fuels them. Berger, a professor in the Department of Biophysics and Biophysical Chemistry at Johns Hopkins University School of Medicine, primarily studies biological nanomachines, which are fueled by the cellular energy currency ATP and carry out coordin...
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P rotein kinases are the workhorses of the cell, orchestrating complex cellular activities by carrying out a relatively simple chemical modification: the transfer of a phosphate molecule from ATP to a protein or lipid substrate via a process called phosphorylation. Kinases are crucial to the function of all living organisms, and deregulated kinase activity lies at the heart of humanity’s most p...
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O n the surface, CharlesNewman’s mathematical research looks abstract, but his models are never far from potential application to the real world. Newman specializes in models of disordered systems that condensed-matter physicists use to understand the behavior of materials as they change phases. His work has also provided insight into apparent discontinuities in the fossil record and the potent...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2006
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0511071103